The commentary discusses the expansion of brain-specific regulatory T cells (Tregs) as a mechanism to mitigate cognitive decline. By modulating inflammation, Tregs support neural integrity and reduce the impact of aging on brain function.
The authors propose that Tregs may serve as therapeutic targets for age-associated cognitive disorders. Expanding their activity could protect against neurodegenerative diseases such as Alzheimer’s.
This perspective reinforces the importance of neuro-immune interactions in maintaining cognitive health and offers insights into novel immunomodulatory therapies.
