Our latest publications from Myelin labs!
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Schwann cells in regeneration and cancer: an epithelial-mesenchymal transition perspective
Journal:
The Royal Society
Publication:
05/03/2025
Type:
review
Category
Tags
HDAC11 deficiency regulates age-related muscle decline and sarcopenia
Journal:
Springer International
Publication:
12/04/2025
Type:
journal-article
Category
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Navigating the transition to Principal Investigator
Journal:
Wiley
Publication:
16/09/2024
Type:
comment
Schwann cell JUN expression worsens motor performance in an amyotrophic lateral sclerosis mouse model
Journal:
Wiley
Publication:
16/08/2024
Type:
journal-article
Schwann Cells as Orchestrators of Nerve Repair: Implications for Tissue Regeneration and Pathologies
Journal:
Cold Spring Harbor Perspectives in Biology
Publication:
03/06/2024
Type:
review
Category
Regulatory T cells limit age-associated retinal inflammation and neurodegeneration
Journal:
Molecular Neurodegeneration
Publication:
05/04/2024
Type:
journal-article
Category
Ageing impairs the regenerative capacity of regulatory T cells in mouse central nervous system remyelination
Journal:
Nature Communications
Publication:
11/03/2024
Type:
journal-article
Category
Glial cell alterations in diabetes-induced neurodegeneration
Journal:
Cellular and Molecurar Life Science
Publication:
18/01/2024
Type:
review
A translational MRI approach to validate acute axonal damage detection as an early event in multiple sclerosis
Journal:
eLife
Publication:
09/01/2024
Type:
journal-article
Category
Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration following peripheral nerve injury
Journal:
EMBO Molecular Medicine
Publication:
07/12/2023
Type:
journal-article
Category
Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration
Journal:
CellPress
Publication:
05/12/2023
Type:
journal-article
Category
Brain-specific regulatory T cell expansion limits cognitive decline
Journal:
Trends in Molecular Medicine
Publication:
20/05/2023
Type:
comment
Category
Tags
SARM1 detection in myelinating glia: sarm1/Sarm1 is dispensable for PNS and CNS myelination in zebrafish and mice
Journal:
Frontiers in Cellular Neuroscience
Publication:
19/05/2023
Type:
journal-article
Category
Novel therapeutic approaches to target neurodegeneration
Journal:
British Journal of Pharmacology
Publication:
26/04/2023
Type:
review
Category
Brain magnetic resonance imaging in the DE50-MD dog model of Duchenne muscular dystrophy reveals regional reductions in cerebral gray matter
Journal:
BMC Neuroscience
Publication:
17/03/2023
Type:
journal-article
Category
Ageing impairs the regenerative capacity of regulatory T cells in central nervous system remyelination
Journal:
bioRxiv
Publication:
25/01/2023
Type:
preprint
Category
Immune–stem cell crosstalk in the central nervous system: how oligodendrocyte progenitor cells interact with immune cells
Journal:
Immunology & Cell Biology
Publication:
03/01/2023
Type:
journal-article
Category
Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration after peripheral nerve injury
Journal:
bioRxiv
Publication:
08/12/2022
Type:
preprint
Category
Tags
Fasciclin 2 engages EGFR in an auto-stimulatory loop to promote imaginal disc cell proliferation in Drosophila
Journal:
PLOS Genetics
Publication:
06/06/2022
Type:
journal-article
Category
Tags
An Experimental Model of Neuro-Immune Interactions in the Eye: Corneal Sensory Nerves and Resident Dendritic Cells
Journal:
International Journal of Molecular Sciences
Publication:
10/03/2022
Type:
journal-article
Emerging Role of HDACs in Regeneration and Ageing in the Peripheral Nervous System: Repair Schwann Cells as Pivotal Targets
Journal:
International Journal of Molecular Sciences
Publication:
10/03/2022
Type:
journal-article
Category
A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair
Journal:
eLife
Publication:
25/01/2022
Type:
journal-article
Category
Autoantibodies and microglia: boon or bane?
Journal:
Brain
Publication:
04/09/2021
Type:
comment
Category
Tags
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun
Journal:
eLife
Publication:
21/01/2021
Type:
journal-article
Category
Tags
Systematic approach to selecting licensed drugs for repurposing in the treatment of progressive multiple sclerosis
Journal:
Journal of Neurology, Neurosurgery and Psychiatry
Publication:
12/11/2020
Type:
journal-article
Category
Aging and Neurodegenerative Disease: Is the Adaptive Immune System a Friend or Foe?
Journal:
Frontiers in Aging Neuroscience
Publication:
23/09/2020
Type:
review
Category
Dynamic CCN3 expression in the murine CNS does not confer essential roles in myelination or remyelination
Journal:
Proceedings of the National Academy of Sciences
Publication:
28/07/2020
Type:
journal-article
Category
Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition
Journal:
Cell
Publication:
20/07/2020
Type:
journal-article
Category
Changes in the oligodendrocyte progenitor cell proteome with ageing
Journal:
Molecular & Cellular Proteomics
Publication:
20/05/2020
Type:
journal-article
Category
Tags
Novel EGR2 variant that associates with Charcot-Marie-Tooth disease when combined with lipopolysaccharide-induced TNF-α factor T49M polymorphism
Journal:
Neurology Genetics
Publication:
03/03/2020
Type:
journal-article
Category
Tags
The fatty acid binding protein FABP7 is required for optimal oligodendrocyte differentiation during myelination but not during remyelination.
Journal:
Glia
Publication:
28/02/2020
Type:
journal-article
Category
Protective and Regenerative Roles of T Cells in Central Nervous System Disorders
Journal:
Frontiers in immunology
Publication:
12/09/2019
Type:
review
Category
Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination.
Journal:
Glia
Publication:
03/04/2019
Type:
journal-article
Category
Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells
Journal:
Frontiers in Cellular Neuroscience
Publication:
27/03/2019
Type:
journal-article
Category
Class IIa HDACs in myelination
Journal:
Aging (Albany NY)
Publication:
05/05/2018
Type:
editorial
Category
Tags
Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells
Journal:
Journal of Cell Biology
Publication:
02/04/2018
Type:
journal-article
Category
Tags
Graded Elevation of c-Jun in Schwann Cells In Vivo: Gene Dosage Determines Effects on Development, Remyelination, Tumorigenesis, and Hypomyelination
Journal:
Journal of Neuroscience
Publication:
13/12/2017
Type:
journal-article
Category
Role of the Excitability Brake Potassium Current I-KD in Cold Allodynia Induced by Chronic Peripheral Nerve Injury
Journal:
Journal of Neuroscience
Publication:
22/10/2017
Type:
journal-article
Category
Tags
After Nerve Injury, Lineage Tracing Shows That Myelin and Remak Schwann Cells Elongate Extensively and Branch to Form Repair Schwann Cells, Which Shorten Radically on Remyelination
Journal:
Journal of Neuroscience
Publication:
13/09/2017
Type:
comment
Category
Tags
Changes in the Coding and Non-coding Transcriptome and DNA Methylome that Define the Schwann Cell Repair Phenotype after Nerve Injury
Journal:
Cell Reports
Publication:
12/09/2017
Type:
comment
Category
Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination
Journal:
Cell Reports
Publication:
01/08/2017
Type:
journal-article
Category
STAT3 Controls the Long-Term Survival and Phenotype of Repair Schwann Cells during Nerve Regeneration
Journal:
Journal of Neuroscience
Publication:
19/04/2017
Type:
journal-article
DOI:
Category
Tags
Vitamin D receptor–retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation
Journal:
Journal of Cell Biology
Publication:
07/12/2015
Type:
journal-article
Category
Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination
Journal:
Brain
Publication:
13/10/2015
Type:
journal-article
Category
Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves
Journal:
Journal of Cell Biology
Publication:
06/07/2015
Type:
journal-article
DOI:
Category
Tags
Epigenetic induction of the Ink4a/Arf locus prevents Schwann cell overproliferation during nerve regeneration and after tumorigenic challenge
Journal:
Brain
Publication:
31/07/2013
Type:
journal-article
Category
Tags
Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer’s disease
Journal:
JCI
Publication:
08/05/2013
Type:
journal-article
Category
L1CAM Binds ErbB Receptors through Ig-Like Domains Coupling Cell Adhesion and Neuregulin Signalling
Journal:
Plos ONE
Publication:
16/07/2012
Type:
journal-article
Category
Tags
Masking of transmembrane-based retention signals controls ER export of gamma-secretase.
Journal:
Traffic
Publication:
04/01/2010
Type:
journal-article
Category
The microbiota regulates murine inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination.
Journal:
PNAS
Publication:
18/11/2009
Type:
journal-article
Category
Sustained Axon-Glial Signaling Induces Schwann Cell Hyperproliferation, Remak Bundle Myelination, and Tumorigenesis
Journal:
Journal of Neuroscience
Publication:
09/09/2009
Type:
journal-article
Category
Tags
Lipid Raft Segregation Modulates TRPM8 Channel Activity
Journal:
Journal of Biological Chemistry
Publication:
30/04/2009
Type:
journal-article
Category
Tags
Transcriptional control of cholesterol biosynthesis in schwann cells by axonal neuregulin 1
Journal:
Journal of Biological Chemestry
Publication:
28/07/2007
Type:
journal-article
Category
Tags
Characterization of a neural-specific splicing form of the human neuregulin 3 gene involved in oligodendrocyte survival
Journal:
Journal of Cell Science
Publication:
01/03/2006
Type:
journal-article
Category
Tags
