CNS PNS PNS - CNS

Regulatory T cells

In our laboratory, we investigate the regeneration and repair of nervous tissue through innovative approaches that integrate advanced cellular biology, neuroimmunology, and emerging therapies. We employ state-of-the-art techniques, including electron and fluorescence microscopy, to further our understanding of neurodegenerative diseases, inflammation, and tissue regeneration. Our publications reflect our commitment to pioneering research, utilising cutting-edge technologies and scientific methodologies.

Alerie Guzman de la Fuente
Jose Antonio Gomez Sanchez
Hugo Cabedo Martí

Academia Adipocytes Ageing Alzheimer’s disease Amyotrophic Lateral Sclerosis Astrocytes Axonal Pathology Chronic denervation Cognitive Decline Cornea Development Diabetes Diabetic Neuropathy Diabetic Retinopathy Duchenne muscular dystrophy Endocytosis Epigenetics Gamma Secretase Glial Cells HDAC11 Immune cells Inflammation Jun Transcription Factor Macrophages Mesenchymal Stem Cells Metabolism Microbiome Microglia Motor Neuron MRI Muller Multiple Sclerosis Muscle atrophy Myelin Myelination Nerve injury Nerve regeneration Nerve repair Neurodegeneration Neuroimmunology Neuroscience Nuclear Receptor Oligodendrocytes OPC´s Pericytes Regeneration Regulatory T cells Remyelination Retina Sarcopenia Schwann Cells Senescence Sod1g93a Mutant Synaptic Plasticity Therapeutic Approaches

Check the latest publications from Myelin Labs about: Regulatory T cells

publication tag: Regulatory T cells

Regulatory T cells limit age-associated retinal inflammation and neurodegeneration

Journal:

Molecular Neurodegeneration

Publication Date:

05/04/2024

Type:

journal-article

Open Access:

https://doi.org/10.1186/s13024-024-00724-w

Category:

CNS

Tags:

Ageing, Inflammation, Neurodegeneration, Regulatory T cells, Retina

Ageing impairs the regenerative capacity of regulatory T cells in mouse central nervous system remyelination

Journal:

Nature Communications

Publication Date:

11/03/2024

Type:

journal-article

Open Access:

https://doi.org/10.1038/s41467-024-45742-w

Category:

CNS

Tags:

Ageing, Multiple Sclerosis, Neuroimmunology, Regulatory T cells

Brain-specific regulatory T cell expansion limits cognitive decline

Brain-specific regulatory T cell expansion limits cognitive decline

Journal:

Trends in Molecular Medicine

Publication Date:

20/05/2023

Type:

comment

Open Access:

https://doi.org/10.1016/j.molmed.2023.05.001

Category:

CNS

Tags:

Ageing, Glial Cells, Regulatory T cells

Ageing impairs the regenerative capacity of regulatory T cells in central nervous system remyelination

Ageing impairs the regenerative capacity of regulatory T cells in central nervous system remyelination

Journal:

bioRxiv

Publication Date:

25/01/2023

Type:

preprint

Open Access:

https://doi.org/10.1101/2023.01.25.525562

Category:

CNS

Tags:

Ageing, Oligodendrocytes, Regulatory T cells, Remyelination

Dynamic CCN3 expression in the murine CNS does not confer essential roles in myelination or remyelination

Dynamic CCN3 expression in the murine CNS does not confer essential roles in myelination or remyelination

Journal:

Proceedings of the National Academy of Sciences

Publication Date:

28/07/2020

Type:

journal-article

Open Access:

https://doi.org/10.1073/pnas.1922089117

Category:

CNS

Tags:

Oligodendrocytes, Regulatory T cells, Remyelination

Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition

Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition

Journal:

Cell

Publication Date:

20/07/2020

Type:

journal-article

Open Access:

https://doi.org/10.1016/j.cell.2020.06.026

Category:

CNS

Tags:

Development, Immune cells, Microglia, Regulatory T cells

Instituto de Investigación Sanitaria y Biomédica de Alicante

(ISABIAL)

Myelin Alicante Labs
Avda Pintor Baeza, 12
Hospital General Universitario Dr Balmis
Planta 6ª Centro de Diagnóstico
03010 Alicante (Spain)

Instituto de Neurociencias

(UMH-CSIC)

Myelin Alicante Labs
Avd. Ramón y Cajal, s/n  
Campus UMH de San Juan.
03550 San Juan de Alicante Alicante (Spain)

+34 965 913 949 hello@myelinalicante.com myelinalicante
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