CNS PNS PNS - CNS

Multiple Sclerosis

In our laboratory, we investigate the regeneration and repair of nervous tissue through innovative approaches that integrate advanced cellular biology, neuroimmunology, and emerging therapies. We employ state-of-the-art techniques, including electron and fluorescence microscopy, to further our understanding of neurodegenerative diseases, inflammation, and tissue regeneration. Our publications reflect our commitment to pioneering research, utilising cutting-edge technologies and scientific methodologies.

Alerie Guzman de la Fuente
Jose Antonio Gomez Sanchez
Hugo Cabedo Martí

Academia Adipocytes Ageing Alzheimer’s disease Amyotrophic Lateral Sclerosis Astrocytes Axonal Pathology Chronic denervation Cognitive Decline Cornea Development Diabetes Diabetic Neuropathy Diabetic Retinopathy Duchenne muscular dystrophy Endocytosis Epigenetics Gamma Secretase Glial Cells HDAC11 Immune cells Inflammation Jun Transcription Factor Macrophages Mesenchymal Stem Cells Metabolism Microbiome Microglia Motor Neuron MRI Muller Multiple Sclerosis Muscle atrophy Myelin Myelination Nerve injury Nerve regeneration Nerve repair Neurodegeneration Neuroimmunology Neuroscience Nuclear Receptor Oligodendrocytes OPC´s Pericytes Regeneration Regulatory T cells Remyelination Retina Sarcopenia Schwann Cells Senescence Sod1g93a Mutant Synaptic Plasticity Therapeutic Approaches

Check the latest publications from Myelin Labs about: Multiple Sclerosis

publication tag: Multiple Sclerosis

Ageing impairs the regenerative capacity of regulatory T cells in mouse central nervous system remyelination

Journal:

Nature Communications

Publication Date:

11/03/2024

Type:

journal-article

Open Access:

https://doi.org/10.1038/s41467-024-45742-w

Category:

CNS

Tags:

Ageing, Multiple Sclerosis, Neuroimmunology, Regulatory T cells

A translational MRI approach to validate acute axonal damage detection as an early event in multiple sclerosis

Journal:

eLife

Publication Date:

09/01/2024

Type:

journal-article

Open Access:

https://doi.org/10.7554/elife.79169

Category:

CNS

Tags:

Axonal Pathology, MRI, Multiple Sclerosis, Neuroscience

Systematic approach to selecting licensed drugs for repurposing in the treatment of progressive multiple sclerosis

Systematic approach to selecting licensed drugs for repurposing in the treatment of progressive multiple sclerosis

Journal:

Journal of Neurology, Neurosurgery and Psychiatry

Publication Date:

12/11/2020

Type:

journal-article

Open Access:

https://doi.org/10.1136/jnnp-2020-324286

Category:

CNS

Tags:

Multiple Sclerosis, Remyelination, Therapeutic Approaches

Protective and Regenerative Roles of T Cells in Central Nervous System Disorders

Protective and Regenerative Roles of T Cells in Central Nervous System Disorders

Journal:

Frontiers in immunology

Publication Date:

12/09/2019

Type:

review

Open Access:

https://doi.org/10.3389/fimmu.2019.02171

Category:

CNS

Tags:

Immune cells, Multiple Sclerosis, Neurodegeneration, Therapeutic Approaches

Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells

Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells

Journal:

Frontiers in Cellular Neuroscience

Publication Date:

27/03/2019

Type:

journal-article

Open Access:

https://doi.org/10.3389/fncel.2019.00085

Category:

CNS

Tags:

Multiple Sclerosis, Oligodendrocytes, Pericytes, Remyelination

Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination

Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination

Journal:

Cell Reports

Publication Date:

01/08/2017

Type:

journal-article

Open Access:

https://doi.org/10.1016/j.celrep.2017.08.007

Category:

CNS

Tags:

Multiple Sclerosis, Oligodendrocytes, Pericytes

Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination

Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination

Journal:

Brain

Publication Date:

13/10/2015

Type:

journal-article

Open Access:

https://doi.org/10.1093/brain/awv289

Category:

CNS

Tags:

Multiple Sclerosis, Nuclear Receptor, Oligodendrocytes, Remyelination

Instituto de Investigación Sanitaria y Biomédica de Alicante

(ISABIAL)

Myelin Alicante Labs
Avda Pintor Baeza, 12
Hospital General Universitario Dr Balmis
Planta 6ª Centro de Diagnóstico
03010 Alicante (Spain)

Instituto de Neurociencias

(UMH-CSIC)

Myelin Alicante Labs
Avd. Ramón y Cajal, s/n  
Campus UMH de San Juan.
03550 San Juan de Alicante Alicante (Spain)

+34 965 913 949 hello@myelinalicante.com myelinalicante
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